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Agmatine vs
As Young remembers, 'We couldnt predict weight loss or weight gain with these drugs.' One of the challenges was that enhanced insulin secretion normally increases body weight
Future progress will likely depend on integrating longitudinal human studies with functional validation, multi-omics analysis, and more precise intervention strategies that target microbial functions and hostmicrobe networks rather than composition alone
This is supported by recent studies from US and German adults with T2D, which reported that the use of GLP-1RAs versus insulin resulted in lower emergency room visits and inpatient admissions but higher drug acquisition costs after treatment initiation [49, 50]
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