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In mammalian cells, glutathione primarily exists in the reduced state at moderate concentrations and in an extremely high proportion, effectively scavenging reactive intermediates produced spontaneously by cells or from external toxic factors, thereby protecting the cells
Acta Neuroveg (Wien)
Front Cell Neurosci 10:56 Knecht T, Borlongan C, dela Pea I (2018) Combination therapy for ischemic stroke: novel approaches to lengthen therapeutic window of tissue plasminogen activator
These pharmacokinetic differences inform the trade-offs in onset, convenience, and dosing convenience
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