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While compounding has filled gaps in shortages and provided a more budget-friendly alternative, it has raised concerns over safety, quality and potential exploitation leading some states to consider legislation to limit or regulate compounding
NICE Technology Appraisal (TA875) recommends semaglutide (Wegovy) only for adults with at least one weight-related comorbidity and a BMI 35 kg/m (or 32.5 kg/m for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean backgrounds)
Therapeutic advances in drug safety 2025
Endocr Rev 1995
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