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Published research has examined its effects on melanogenesis, UV-induced DNA damage, and melanocyte proliferation in various experimental systems

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Additionally, approximately 10% of oral melanomas are amelanotic, which may result in diagnostic difficulties, and immunohistochemistry is indicated.4,7 Actinic cheilitis Actinic cheilitis is a potentially malignant condition of the lower lip vermilion resulting from chronic exposure to UV radiation