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When REDEFINE 4 results are published, they will provide the first and only direct comparison between these two treatments using the same population, the same endpoints, and the same measurement protocols

The metabolic programs identified in this study were inferred from transcriptomic data

When GSH was tested together with reduced PfGrx C88S or PfGrx C32S/C88S , the syringe of the stopped-flow spectrofluorometer also contained 0.4 U/mL glutathione reductase (GR) and 0.25 mM NADPH to ensure the removal of trace amounts of GSSG that might interfere with the redox measurements

Males typically have more body water than females of the same weight, which is why the gender constant differs