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doi: 10.3389/fnut.2021.765809 Summary Keywords combination therapy, glutamine metabolism, immune microenvironment, metabolic reprogramming, tumors Citation Fang L, Gao D, Jiang Z, Li G and Li M (2025) Glutamines double-edged sword: fueling tumor growth and offering therapeutic hope

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We then applied this signature in STEP 2, an external validation set, in which it showed similar performance for distinguishing semaglutide treatment from placebo (AUC = 0.93) (Extended Data Fig

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